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25mg Clindamycin oral drops for the treatment of wounds and abscesses in cats and dogs

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Active Substances and Other Ingredients: One ml contains: Active substance: Clindamycin 25mg (as Clindamycin Hydrochloride 27.15 mg) Excipients: Ethanol 90.56mg. Clear, colourless solution. Indications: For the treatment of wounds and abscesses in cats and dogs. Dosage and Administration: For oral administration. Recommended dosage: For cats and dogs: 5.5mg/kg for dental infections wounds, and abscesses every 12 hours for 7-10 days and up to 28 days. If no clinical response is seen within 4 days, re-determine the diagnosis. Advice on Correct Administration A 10ml graduated syringe is provided to facilitate the administration of the veterinary medicinal product. Contraindications: Do not use in neonatal animals. Adverse Reactions: Vomiting and diarrhoea are occasionally observed. Clindamycin sometimes causes the overgrowth of non-sensitive organisms such as resistant Clostridia and yeasts. If super-infection occurs, the treatment should be stopped and appropriate measures should be taken based on the clinical situation. If you notice any serious effects or other effects not mentioned, please inform your veterinary surgeon. Presentation: Carton box of one bottle of 22ml. Special Warnings: Special precautions for use in animals Do not use in rabbits, hamsters, guinea pigs, chinchillas, horses or ruminants because ingestion of clindamycin by these species may cause severe gastrointestinal disorders. Do not use in case of hypersensitivity to either clindamycin or lincomycin, or to any of the excipients. Inappropriate use of the product may increase the prevalence of bacteria resistant to clindamycin. Before use of the product, the identification of causative pathogenic micro-organisms should be carried out and their susceptibility to clindamycin should be established. Clindamycin shows parallel-resistance with lincomycin and co-resistance with erythromycin. There is a partial cross-resistance to erythromycin and other macrolides. During prolonged therapy of one month or greater, tests for liver function and renal function and blood counts should be performed periodically. In case of administration of high doses of clindamycin it is recommended to monitor blood parameters during the treatment period. In dogs and cats with kidney problems and/or liver problems, accompanied by severe metabolic aberrations, the dose to be administered should be carefully determined and their condition should be monitored by performing serum tests during treatment. Special precautions to be taken by the person administering the medical product to animals Wash hands after administration. People with known hypersensitivity to lincosamides (lincomycin and clindamycin) should avoid contact with the veterinary medicinal product. In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician. Use during pregnancy, lactation or lay While high dose studies in rats suggests that clindamycin is not a teratogen and does not significantly affect the breeding performance of males and females, the safety of the veterinary medicinal product in gestating bitches/queens or breeding male dogs/cats has not been established. Use only accordingly to the benefit/risk assessment by the responsible veterinarian. Clindamycin can pass the blood-milk barrier. As a consequence, treatment of lactating females can cause diarrhoea in puppies. Interaction with other medicinal products and other forms of interaction Neuromuscular blocking effects were observed with clindamycin, which may possibly enhance the activity of other neuromuscular blocking agents. The simultaneous use of such products must be made with caution. Do not use clindamycin together with chloramphenicol or macrolides as they share the same binding site on the ribosomes. During the simultaneous use of clindamycin and aminoglycosides (e.g. gentamicin), the risk of adverse interactions (acute renal failure) cannot be excluded. Clindamycin may reduce the levels of cyclosporine, concomitant use should be avoided. Overdose (symptoms, emergency procedures, antidotes), if necessary Doses of 300mg/kg were tolerated by dogs without having adverse effects. Vomiting, loss of appetite, diarrhoea, leukocytosis and elevations in liver enzymes (AST, ALT) were observed occasionally. In such cases, discontinue treatment immediately and establish a symptomatic treatment. Incompatibilities Do not mix this product with any other veterinary medicinal products. Special precautions for the disposal of unused product or waste materials, if any: Medicines should not be disposed of via wastewater or household waste. Ask your veterinary surgeon how to dispose of medicines no longer required. These measures should help to protect the environment. Special storage precautions: Keep out of the reach and sight of children. Do not use after the expiry date stated on the carton after EXP. Shelf life after first opening the container: 28 days. ACVM No A011249 See www.foodsafety.govt.nz/acvm Clindacure For Animal Treatment Only RESTRICTED VETERINARY MEDICINE

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